Connect with us


World’s first vaccine for deadly swine fever



World's first vaccine for deadly swine fever

Vaccines against African swine fever being tested in Vietnam are close to approval, global and US veterinary officials said, in what would be a major breakthrough to tackle the deadly animal disease that regularly ravages pig farms worldwide.

African swine fever has for years disrupted the $250 billion global pork market. In the worst outbreak in 2018–19, about half the domestic pig population died in China, the world’s biggest producer, causing losses estimated at over $100 billion.

After decades of failed attempts due to the complexity of the virus, two vaccines co-developed by US scientists and being tested in large pilot schemes by Vietnamese companies are showing “very promising” results, Gregorio Torres, head of the science department at the World Organisation for Animal Health (WOAH), told reporters in a telephone interview.

“We have never been so close to getting a vaccine that may work,” Torres said, noting the two shots had “probably the highest chances to succeed” and be authorised for sale worldwide.

Both vaccines have received approval in Vietnam for pilot commercial use, which is now complete. The next step will be nationwide authorization, the first ever for an African swine fever injection, and possible sales overseas.


US Agriculture Secretary Thomas Vilsack said there was likely to be interest in precautionary purchases in the United States, despite the country having so far been spared from the virus.

“There will be a specific interest, obviously,” Vilsack said in an interview with newsmen in April, speaking about possible purchases of the Vietnamese vaccines.

The vaccines were tested in Vietnam, where swine fever is a constant threat, because they could not be developed in the U.S. as the virus is not present there.

Since 2021, swine fever, which is not deadly to humans, has been reported in nearly 50 countries and caused about 1.3 million pig deaths, WOAH said in a regular report last week.

Currently, there are no major outbreaks, but agribusiness lender Rabobank warned in April that the possible spread of the disease, especially in China, remained among the top risks to the global pork industry.


No Safety Issues

Researchers at the United States Department of Agriculture have reviewed the results of one of the vaccines, NAVET-ASFVAC, which they co-developed with Vietnamese company NAVETCO (VET.HNO), a USDA spokesperson said.

After the vaccine showed a high, level of efficacy and no safety risks in trials, 600,000 doses were approved for initial sales to pig farmers in Vietnam, of which the first 40,000 “have been delivered without any safety problems,” the USDA said.

That followed an initial hiccup when use of the injection was suspended after dozens of pigs died last summer following inoculations on farms that used the vaccine off-label, the USDA said, administering it to hogs that were not supposed to be inoculated, such as pregnant sows.


No problems emerged after deliveries resumed with adequate veterinary monitoring, the USDA said.

NAVET-ASFVAC is an attenuated live-virus injection, like those used in children’s routine vaccinations around the world. In past years, the use of unlicensed live-virus injection in China raised concerns that they caused the emergence of new strains of swine fever.

Only limited data are available from China’s trials on a live-virus injection against swine fever.

The second vaccine tested in Vietnam, AVAC ASF LIVE, which was discovered by US researchers and commercialized by Vietnamese firm AVAC, has been delivered to more pigs than NAVET-ASFVAC under its pilot deployment, but USDA said it had not yet reviewed the data.


NAVETCO, AVAC, and Vietnam’s agriculture ministry, which is responsible for the approval of veterinary vaccines, did not respond to requests for comment.


Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Copyright © 2016 - 2022 ChronicleNG