Arsenal will face Liverpool in the semi-finals of the Carabao Cup, while Chelsea will meet Tottenham.
Chelsea’s meeting with Spurs is a repeat of the 2015 final, when the Blues won 2-0 at Wembley.
Both semi-finals are scheduled to take place over two legs – with the first of each played in the week commencing 3 January 2022.
The deciding legs will take place in the week commencing 10 January, with the final at Wembley on 27 February.
Eight-time winners Liverpool came from 0-2 and 1-3 down to make it 3-3 before they beat Leicester 5-4 on penalties in a thrilling quarter-final on Wednesday.
The Reds have not won the competition since 2012.
Arsenal, 5-1 winners over Sunderland on Tuesday, have lost three finals since their last League Cup triumph in 1993.